Research of Interest

Lung Foundation Australia regularly scans other sources to keep up-to-date about developments of interest.

This page brings together some of the interesting and reputable respiratory research being undertaken by external bodies.

Immunogenicity of influenza vaccination in patients with Chronic Obstructive Pulmonary Disease (COPD)

8th March 2017

The Princess Alexandra Hospital and Mater Hospital in Brisbane and the Royal Melbourne Hospital are seeking men and women with COPD and those with healthy lungs to participate in an influenza research study.

Influenza infection is a frequent and important problem in COPD.  Influenza can have severe consequences in these patients, leading to acute exacerbations of COPD, pneumonia and respiratory failure.  COPD patients are thus recognised as a group at particular risk of influenza and current guidelines recommend yearly influenza vaccination.  It has been suggested that people with COPD may have an aberrant immune response to influenza viruses and as such, they may be less able to effectively mount an immune response to influenza vaccination.

Aim of the study

The aim of the study is to find out how the vaccine affects the immune system in different people and why it works better in some people than others.

Who can participate?

If you are aged between 50 and 85, with or without COPD, and have not already had your influenza vaccination for 2017, you are invited to take part in this research project.

If you have already received your influenza vaccination in 2017 you can register your interest for participation in 2018.

For more information, contact the Respiratory Research Nurse at the study sites:

The study is supported by a National Health and Medical Research Council grant.  The study has the approval of the Human Research and Ethics Committee, Princess Alexandra Hospital HREC/09/QPAH/297 and Royal Melbourne Hospital HREC.2015.059

A Clinical Trial in COPD

17 January 2017 

A clinical trial to assess the relief of breathlessness using low-dose morphine is currently underway by the Australian Palliative Care Clinical Studies Collaborative (PaCCSC). This study will build on previous work of the Collaborative. It will test how effective different ranges of low-dose morphine capsules taken each morning are when compared with placebo in relieving breathlessness.

The study, led by Professor David Currow, Chief Investigator, Palliative and Supportive Services, Flinders University, is nicknamed BEAMS and is short for Breathlessness, Exertion and Morphine Sulphate.

The BEAMS Study is looking for eligible people with COPD to take part. If you are:

• Breathless doing day-to-day things despite the underlying causes being treated, and
• On stable medications and not taking morphine, you may be eligible.

If you live in Adelaide, Sydney, Newcastle, Melbourne, Geelong, Brisbane or Nambour and are willing/able to attend clinic visits, please contact PaCCSC on 08 8275 1926 or email PaCCSC@flinders.edu.au.