If you are living with Chronic Obstructive Pulmonary Disease (COPD), there are many potential benefits, for yourself and others, of taking part in a clinical trial.
The Preventing Adverse Cardiac Events (PACE) in COPD clinical trial, at sites around Australia, New Zealand and eventually India, will investigate the impact of heart disease drug treatment for people living with COPD, and whether this treatment can reduce cardiac events.
The drug in the study, bisoprolol, is a beta-blocker which causes the heart to beat slower and less forcefully, therefore lowering blood pressure and workload on the heart.
Professor Christine Jenkins AM, Lung Foundation Australia Chair, leading respiratory physician and chief investigator of the PACE trial, said about 50 per cent of people living with COPD died from heart disease, not their lung condition.
“In the majority of these people, their heart disease was either not recognised or not treated as a major clinical problem,” Prof Jenkins said.
“We hope this trial can have extremely important outcomes. It may identify an easily available, well tolerated and effective medication to reduce deaths, hospitalisations and even flare-ups.”
Prof Jenkins said while certain drugs had been regarded as unsafe for people living with COPD, this dated back to before it was properly understood that asthma and COPD were very different diseases.
“Even if they manifest in the same way, they have a very different underlying pathology,” she said.
“Many reviews have shown certain drugs can be safe but COPD patients have been excluded from some of these studies.”
The George Institute for Global Health’s PACE trial needs 1150 participants. The requirements for participants include:
- Aged 40-85
- Living with COPD and have had a flare-up/exacerbation in past 24 months
- Must not have asthma
- Deemed medically suitable by the study doctor
- Willing to attend hospital and clinic visits.
To take part in the Preventing Adverse Cardiac Events in Chronic Obstructive Pulmonary Disease (COPD) study, to find a location near you, or to find out more, email firstname.lastname@example.org