The Anti-fibrotic Treatments for Pulmonary Fibrosis (PF) fact sheet by Lung Foundation Australia offers essential guidance on managing PF with medications like pirfenidone and nintedanib. These anti-fibrotic drugs are prescribed for individuals diagnosed with Idiopathic Pulmonary Fibrosis (IPF) or other forms of progressive PF, aiming to slow lung scarring and preserve lung function. It is important to discuss your options with your specialist doctor who will help you choose the medication that best suits your situation.
While PF currently has no cure, these medications can help improve quality of life by reducing disease progression. Treatment decisions are tailored to each patient based on factors such as lung function, lifestyle, and coexisting medical conditions. When you are taking these types of medications, it is crucial to follow your specialist’s instructions regarding dosage and timing—typically, tablets should be taken with meals to reduce gastrointestinal side effects.
Like most medications, anti-fibrotics may cause some side effects, although most people will not experience them. Common side effects include nausea, diarrhoea, appetite loss, weight loss, liver function abnormalities, and sun-related skin rashes. Pirfenidone may increase sensitivity to sunlight, while nintedanib is more likely to cause diarrhoea. To manage these effects, patients are advised to stay hydrated, eat smaller low-fibre meals, avoid spicy or fatty foods, and use sun protection like SPF50+ sunscreen and protective clothing.
Regular blood tests are necessary to monitor liver function, and ongoing check-ups help track lung health. Patients should work with their healthcare team to create a personalized side effect management plan, which may include medications for nausea or diarrhoea. The type of antifibrotic medication for treatment depends on factors such as lifestyle, lung function, and other medical conditions. Your specialist doctor will help determine the most suitable medication for your situation.”
Support is available through Lung Foundation Australia, which offers educational resources, peer support, and access to clinical trials. For more information, visit lungfoundation.com.au or call 1800 654 301.
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